All Topics

Tribal Health

Health programs for Native American and tribal communities.

31 open grants
HHS-SAMHS-SAMHSA
TI-26-018

Emergency Department Alternatives to Opioids

The purpose of the program is to establish and implement practices which will help organizations develop alternatives to pharmacological opioid interventions for pain, reduce the potential harmful consequences of opioid use for pain care in hospitals and emergency departments, thereby promoting safer pain treatment and reducing the risk of future opioid misuse and possible opioid overdose.

HHS-SAMHS-SAMHSA
TI-26-012

Tribal Opioid Response

The purpose of the TOR program is to assist in addressing the opioid overdose crisis in Tribal communities by increasing access to FDA-approved medications for opioid use disorder, and supporting the continuum of prevention, treatment, and recovery support services for opioid use disorder and co-occurring substance use disorders. This program also supports prevention, treatment, and recovery support services for stimulant misuse and use disorders, including those involving cocaine and methamphetamine.

HHS-SAMHS-SAMHSA
SM-26-006

Trauma-Informed Services in Schools

The purpose of this program is to increase student access to evidence-based support services and mental health care by developing innovative initiatives, activities, and programs to link local school systems with local trauma support and mental health services. Note: At least one award will be made to tribes or tribal organizations pending adequate application volume.

HHS-CDC-NCCDPHP
CDC-RFA-DP-26-0227

Public Health Strategies to Address Alzheimer's Disease and Related Dementias: The National Healthy Brain Initiative, BOLD Public Health Centers of Excellence, and Public Health Adoption Accelerator

Alzheimer's disease, the most common form of dementia, is a progressive condition. It begins with mild memory loss and may lead to the inability to communicate or respond to one's environment. Its prevalence is rising with the aging U.S. population. In 2021, it was the 5th leading cause of death for those 65 and older, with death rates continuing to climb. The CDC Alzheimer's Disease Program, through the National Healthy Brain Initiative (HBI) and funded partners, promotes brain health, addresses cognitive impairment, and supports caregivers using evidence-based approaches. This funding opportunity aligns with the HBI Road Map Series (including the State and Local Road Map 2023–2027 and the Road Map for Indian Country) and fulfills the aims of the Building Our Largest Dementia (BOLD) Infrastructure for Alzheimer’s Act (P.L. 115-406). Funding Structure: Component 1: National Healthy Brain Initiative: Funds up to two (2) organizations to develop and implement public health strategies guided by the HBI Road Map Series. Funded organizations will: Develop evidence-informed training for health care and public health professionals on ADRD and caregiving. Expand the availability and use of public health surveillance data, including adaptation & revision of the Behavioral Risk Factor Surveillance System (BRFSS) subjective cognitive decline and caregiver optional modules. Facilitate the coordination of recipients and national partners to address ADRD. Funding range: $2,500,000 to $3,000,000 per 12-month budget period. Component 2: BOLD Public Health Centers of Excellence: Funds three (3) Centers, each specializing in one of three topic-specific areas: dementia risk reduction, early detection and management of dementia, or dementia caregiving. Centers will: Support the needs of the BOLD public health program and other public health agencies. Identify, disseminate, and promote best practices. Translate promising research into practical tools and resources. Increase professional education and develop materials to address specific individual needs to improve health outcomes. Funding range: $750,000 to $1,000,000 per 12-month budget period. Component 3: ADRD Public Health Adoption Accelerator. Funds up to two (2) organizations to serve as public health strategy adaptation accelerator programs. This means using dissemination and implementation of science to spread and put into practice effective public health strategies, tools, and resources to tackle ADRD. Organizations will: Collaborate with CDC and other organizations to create a prioritized list of ADRD approaches & strategies. Use proven strategies to engage partners, health care organizations, and policymakers to enhance uptake and implementation, accelerating the impact of ADRD efforts. Provide technical assistance to Component 1 & 2 recipients. Funding range: $750,000 - $1,200,000 per 12-month budget period. Applicants may apply for multiple components, but must submit a separate application per component.

99 days left
USDOJ-OJP-OJJDP
O-OJJDP-2025-172516

OJJDP FY25 Juvenile Drug Treatment Court Program

This NOFO will support states, state and local courts, units of local government, and federally recognized Tribal governments to implement new and enhance existing juvenile drug treatment courts (JDTCs) to improve outcomes for youth with substance use disorders or co-occurring substance use and mental health disorders.

Up to $1.0M34 days left
USDOJ-OJP-OJJDP
O-OJJDP-2025-172515

OJJDP FY25 Family Treatment Court Program

This NOFO will support state and local courts, units of local government, and federally recognized Tribal governments to establish new, enhance existing, or implement statewide or countywide family treatment courts to ensure the provision of substance use treatment and other services that improve child, parent, and family outcomes.

Up to $2.0M34 days left
HRSA
HRSA-26-070

Regional Pediatric Prevention Network

The purpose of this program is to support a Regional Pediatric Prevention Network (RPPN). The RPPN strengthens local and regional capacity to care for children during disasters and emergencies through community partnerships, coordinated pediatric preparedness, and dissemination of research-informed pediatric disaster care. The RPPN will include at least 10 children’s hospitals, or their university pediatric partners, funded through two primary awards. It will also include community partners working with these hospitals. Each of the 10 Children’s Hospital centers will advance pediatric emergency and disaster preparedness at the local, regional, and national levels, including for children with special health care needs and behavioral health concerns, children living in poverty, and children in rural, remote, and tribal areas.

Up to $11.3M83 days left
HRSA
HRSA-26-104

Transforming Pediatrics for Early Childhood (TPEC) Program

The Transforming Pediatrics for Early Childhood Program (TPEC) will advance the U.S. Department of Health and Human Services’ Make America Healthy Again (MAHA) priorities by preventing chronic disease early in life and promoting healthy development in early childhood. TPEC recipients - organizations with statewide or tribal reach - will place early childhood development (ECD) experts in local pediatric practices to deliver team-based care to young children and their families. Recipients will improve the quality and cost effectiveness of pediatric primary care by delivering a comprehensive team-based approach that focuses on factors critical to child development. Through this approach, pediatric primary care staff will:   ​Screen families for their needs related to mental health, housing, nutrition, and child development;  ​Build safe, stable, and nurturing relationships between caregivers and their children;  ​Educate caregivers on developmental milestones and how to watch for them; and  ​Make sure that families get referrals and access to additional or specialized support.   TPEC recipients will: Place early childhood development (ECD) experts in pediatric practices that primarily serve families covered by Medicaid/Children’s Health Insurance Program (CHIP) and deliver high-quality ECD services using a team-based approach.Build the skills of pediatric primary care staff statewide to deliver high-quality ECD services using a team-based approach. Improve statewide administrative policies and financing strategies to expand and sustain team-based pediatric primary care, improving the standard of care for all young children. TPEC will result in measurable improvements in service delivery rates and early childhood development outcomes.

Up to $950K113 days left
USDOJ-OJP-BJA
O-BJA-2025-172542

BJA FY25 Edward Byrne Memorial Justice Assistance Grant (JAG) Program – Local Formula

OJP is committed to advancing work that furthers DOJ’s mission to uphold the rule of law, to keep our country safe, and to protect civil rights. OJP provides federal leadership, funding, and other critical resources to directly support law enforcement, combat violent crime, protect American children, provide services to American crime victims, and address public safety challenges, including human trafficking and the opioid crisis. With this Notice of Funding Opportunity (NOFO), BJA seeks to award Edward Byrne Memorial Justice Assistance Grant (JAG) Program funds to eligible units of local government and tribal governments. Prospective applicants should check the FY25 JAG allocations to determine if they are eligible to receive direct JAG funding from BJA prior to starting an application: https://bja.ojp.gov/program/jag/allocations. For more information on the JAG Program, please see: https://bja.ojp.gov/program/jag/overview.

Up to $4.1M28 days left
HHS-CDC-NCIPC
CDC-RFA-CE-26-0061

Drug-Free Communities (DFC) Support Program – NEW (Year 1)

The Drug-Free Communities (DFC) Support Program was created by the Drug-Free Communities Act of 1997 (Public Law 105-20). The Executive Office of the President, Office of National Drug Control Policy (ONDCP), and the Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), National Center for Injury Prevention and Control (NCIPC) are accepting applications for Fiscal Year (FY) 2026 Drug-Free Communities (DFC) Support Program grants. The purpose of the DFC Support Program is to establish and strengthen collaboration to support the efforts of community coalitions working to prevent youth substance use. By statute, the DFC Support Program has two goals: 1) Establish and strengthen collaboration among communities, public and private non-profit agencies, as well as federal, state, local, and tribal governments to support the efforts of community coalitions working to prevent and reduce substance abuse among youth (individuals 18 years of age and younger). 2) Reduce substance abuse among youth and, over time, reduce substance abuse among adults by addressing the factors in a community that increase the risk of substance abuse and promoting the factors that minimize the risk of substance abuse.

Up to $125K21 days left
HHS-CDC-NCIPC
CDC-RFA-CE21-210206CONT26

Drug-Free Communities (DFC) Support Program – COMPETING CONTINUATION (Year 6)

The Drug-Free Communities (DFC) Support Program was created by the Drug-Free Communities Act of 1997 (Public Law 105-20). The Executive Office of the President, Office of National Drug Control Policy (ONDCP), and the Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), National Center for Injury Prevention and Control (NCIPC) are accepting applications for Fiscal Year (FY) 2026 Drug-Free Communities (DFC) Support Program Grants. The purpose of the DFC Support Program is to establish and strengthen collaborations to support the efforts of community coalitions working to prevent and reduce substance use among youth. By statute, the DFC Support Program has two goals: 1) Establish and strengthen the collaboration among communities, public and private non-profit agencies, as well as federal, state, local, and tribal governments to support the efforts of community coalitions working to prevent and reduce substance use among youth (individuals 18 years of age and younger). 2) Reduce substance use among youth and, over time, reduce substance use among adults by addressing the factors in a community that increase the risk of substance use and promoting the factors that minimize the risk of substance use. This funding opportunity will fund applicants who have concluded the first (Year 1 – 5) funding cycle or have experienced a lapse in funding.

Up to $125K21 days left
USDOJ-OJP-BJA
O-BJA-2025-172486

BJA FY25 Public Safety and Mental Health Initiative

This NOFO supports comprehensive service networks addressing untreated mental illness and substance use at the intersection of mental health, substance use, and justice systems. This program responds to the growing burden of endemic vagrancy, disorderly behavior and public safety threats faced by law enforcement agencies. These agencies are often positioned as first responders to situations better addressed by health and social service systems. Law enforcement and justice agencies nationwide need actionable alternatives that prioritize both public order and appropriate treatment settings for those experiencing mental illness or substance use disorders. Specifically, this initiative provides funding to support activities through four core areas: (1) crisis stabilization centers; (2) treatment services; (3) housing access; and (4) electronic health record (EHR) systems and technology modernization.

Up to $3.0M6 days left
HHS-SAMHS-SAMHSA
FG-26-003

FY2026 Support for 988 Tribal Response Cooperative Agreements

The purpose of the 988 Tribal Response program is to improve connection and response to 988 contacts (including calls, chats, and texts) originating in Tribal communities and/or initiated by American Indians/Alaska Natives.

HHS-ACL
HHS-2026-ACL-AOA-OIRC-0018

U.S. Administration on Aging, National Resource Centers on Older Indians, Alaska Natives and Native Hawaiian Programs

The primary goal of the Native American Resource Center (NARC) will be to enhance the knowledge about older adults in American Indian, Alaskan Native, and Native Hawaiin (AI/AN/NH), community, thereby increase and improve the delivery of services to elders. The NARC will focus on the development and provision of technical information. The NARC's will have a national focus and direct its resource to one or more of the primary concerns in their application which includes health issues, long term care, including in-home care; elder abuse; and other problems and issues facing AI, AN and NH older populations. The NARC's objective will be to 1) gather information, 2) performance research, and 3) provide dissemination of results of research and provide technical assistance and training, to entities that provide services to the targeted older adult population in the AI, AN, and NH communities. Applicants should include anticipated program outcomes, how the outcomes will be measured, and the overall success of the program/activities and how they will be determined.

Up to $340K36 days left
HHS-SAMHS-SAMHSA
SM-26-005

Project AWARE (Advancing Wellness and Resiliency in Education)

The purpose of Project AWARE is to develop a sustainable infrastructure for school-based mental health programs and services. Award recipients should build collaborative partnerships with the State Education Agency, Local Education Agency, Tribal Education Agency, the State Mental Health Agency, community-based providers of behavioral health care services, school personnel, community organizations, families, and school-aged youth.

HHS-SAMHS-SAMHSA
SM-26-010

Garrett Lee Smith State/Tribal Youth Suicide Prevention and Early Intervention Program

The purpose of this program is to support States and Tribes in implementing suicide prevention and early intervention strategies for youth, up to the age of 24 years, in schools, educational institutions, juvenile justice systems, substance use and mental health programs, foster care systems, pediatric health programs, and other child- and youth-serving organizations.

HHS-ACL
HHS-2026-ACL-AOA-DASG-0012

Disaster Assistance for State Units on Aging (SUAs) and Tribal Organizations

Grants awarded under this announcement are to provide disaster reimbursement and assistance funds to those State Units on Aging (SUAs), and federally recognized Tribal Organizations who are currently receiving a grant under Title VI of the Older Americans Act (OAA), as amended. Total funding available for disaster assistance is subject to the availability of funds appropriated. The estimated number of awards is seven with a one year project period. Funds may only be used in those areas designated in the Major Disaster Declaration issued by the President of the United States under the Robert T. Stafford Relief and emergency Assistance Act. Funds typically are for the following OAA Title III types of gap-filling services: outreach, information and assistance, counseling, case management, advocacy on behalf of older persons, additional food and meals, supplies, damaged senior center equipment replacement, staff overtime, emergency medications, transportation and other such immediate needs. OAA funds may be sed for permissible expenses incurred which are not or cannot be paid for through other disaster funding resources. Applicants should talk with State, Tribal, and local Emergency Managers to determine what funds may be available through other resources before applying for OAA funding. Eligible SUAs and Title VI grantees should discuss all disaster applications including amount of funds requested with ACL contacts prior to submitting a formal application. SUAs, and federally recognized Tribal Organizations currently receiving a grant under Title VI of the OAA must submit proposals electronically via http://www.grants.gov.

Up to $600K161 days left
HHS-ACL
HHS-2026-ACL-CIP-ATTF-0067

Assistive Technology Alternative Financing Program

The purpose of the Assistive Technology (AT) Alternative Financing Program (AFP) is to support programs that provide for the purchase of AT, such as a low-interest loan fund, an interest buy-down program, a revolving loan fund, a loan guarantee, or an insurance program, that results in the acquisition of AT devices and services.  Applicants for the AT AFP grant awards are required to provide an assurance that, and information describing the manner in which, the AT AFP will expand and emphasize consumer choice and control.  Applicants should incorporate credit-building activities in their programs, including financial education and information about other possible funding sources.  Successful applicants must emphasize consumer choice and control and build programs that will provide financing for the full array of AT devices and services and ensure that all people with disabilities, regardless of type of disability or health condition, age, level of income, and residence, have access to the program.

Up to $700K14 days left
HHS-CDC-GHC
CDC-RFA-JG-26-0051

Strengthening global health security in India to contain public health threats and accelerate outbreak response

This NOFO’s purpose is to support district, state and national public health systems in India to advance GHSA priorities to prevent, detect and respond to infectious disease threats. CDC will work with the Government of India (GoI) to strengthen capacity to control disease outbreaks at their source and neutralize public health threats. This NOFO will augment and increasingly transition CDC-supported GHSA initiatives to GoI institutions including the National Centre for Disease Control, National Health Mission, Indian Council of Medical Research, National Disaster Management Authority, National Institute of Disaster Management and All Indian Institute of Medical Science. The core aim is to enhance India’s public health capacity through a One Health approach in alignment with the International Health Regulations in five key areas: 1) public health workforce; 2) disease surveillance; 3) laboratory systems; 4) emergency preparedness and response; and 5) antimicrobial resistance.

93 days left
IHS
HHS-2026-IHS-ALZ-0001

Addressing Dementia in Tribal and Urban Indian Communities: CAReS Program

This Notice of Funding Opportunity (NOFO) supports Tribal and Urban Indian communities in strengthening dementia care and services for American Indian and Alaska Native (AI/AN) people. Rooted in Indigenous values and community self-determination, the program will fund meaningful, measurable improvements that span the full dementia care continuum, from early recognition to caregiver support. Option A – Dementia CAReS (Care Access, Resources, and Support). One national awardee will coordinate four integrated priorities: Mini-Project Funding to help clinics launch culturally tailored services. A Dementia Champion Network connecting frontline leaders. Success Sharing through case studies and toolkits. Evaluation & Data using common performance measures and dashboards. Option B – Dementia Caregiver Support and Training Center. One national awardee will deliver dementia caregiver support training, services, resources, and technical assistance. Services will support Tribes, Tribal organizations, and Urban Indian organizations. The awardee will develop and implement a comprehensive, culturally relevant caregiver support and training model. It will prioritize leadership and advocacy, caregiver support, and knowledge and skills development. Across both options, recipients will document emerging practices using standardized measures. These measures will guide continuous quality improvement and improve outcomes for AI/AN people and their caregivers. Across both options, recipients will document emerging practices using standardized measures. These measures will guide continuous quality improvement and improve outcomes for AI/AN people and their caregivers. Funding range for Option A (CAReS) per applicant for the first budget period: ​$500,000 to $750,000 Funding range for Option B (Caregiver Support) per applicant for the first budget period: ​$250,000 - $300,000​​ We expect to fund projects in 5 one-year budget periods for a total period of performance of 5 years.

69 days left
IHS
HHS-2026-IHS-EP1-0001

Epidemiology Program for American Indian/Alaska Native Tribes and Urban Indian Communities

The purpose of this NOFO is to strengthen public health capacity of 1) Tribal Epidemiology Centers (TECs) and 2) the Tribes, Tribal Organizations, Urban Indian organizations, and Intertribal Consortiums that they support to fulfill the seven functions of TECs as outlined in the Indian Health Care Improvement Act (IHCIA) at 25 U.S.C. 1621m(b). It is the intent of IHS to fund sufficient TECs to serve Tribes and Urban Indian communities in all 12 IHS administrative areas and serving the Urban population as a consolidated Area. Applicant objectives may include activities beyond the required activities but must address all required activities.

24 days left
IHS
HHS-2026-IHS-TSGP-0001

Tribal Self-Governance Planning

The TSGP allows Tribes to negotiate with the IHS to assume Programs, Services, Functions, and Activities (PSFAs), in whole or in part. This gives Tribes the authority to manage and tailor health care programs to best suit the needs of their communities. Participation in the TSGP gives Tribes flexibility to tailor their health care needs by choosing one of three ways to get health care from the Federal Government for their citizens. Tribes can choose to: Get health care services directly from the IHS.Contract with the IHS to administer individual programs and services the IHS would otherwise provide (referred to as Title I Self-Determination Contracting).Compact with the IHS to assume control over health care programs the IHS would otherwise provide (referred to as Title V Self-Governance Compacting or the TSGP).These options are not exclusive. Tribes may choose to combine options based on their individual needs and circumstances. This Planning Cooperative Agreement’s purpose is to provide resources to: Tribes interested in entering the TSGP.Existing Self-Governance Tribes interested in assuming new or expanded PSFAs

58 days left
IHS
HHS-2026-IHS-NIHOE-0001

National Indian Health Outreach and Education

The National Indian Health Outreach and Education (NIHOE) Program is a competitive cooperative agreement. The NIHOE Program was established to provide health outreach and education efforts to American Indians and Alaska Natives.

3 days left
IHS
HHS-2026-IHS-TMD-0001

Tribal Management Grant (TMG) Program

The Tribal Management Grant (TMG) Program is a competitive grant program offering capacity building and developmental support for federally recognized Indian Tribes and Tribal Organizations (T/TOs). The TMG Program was established to help T/TOs prepare for assuming all or part of existing IHS programs, functions, services, and activities (PFSAs) and further develop and improve Tribal health management capabilities. The program has been available since shortly after enactment of the Indian Self-Determination and Education Assistance Act of 1975 (ISDEAA) in 1975.

3 days left
IHS
HHS-2026-IHS-ETHIC-0001

Ending the HIV/HCV Epidemics in Indian Country

The purpose of this program is to support communities to directly increase the diagnoses, treatment, and prevention of HIV, HCV, and syphilis. Successful applicants will work toward a re-duction of new HIV infections and relevant co-morbidities, specifically syphilis and HCV infections; improve HIV/HCV/syphilis-related health outcomes; and reduce HIV/HCV/syphilis-related health disparities among the AI/AN population. In four separate but related parts, this initiative aims to implement effective and innovative strategies, interventions, approaches, and services to reduce new HIV/HCV/syphilis infections among AI/AN communities in the U.S. This initiative’s overarching goals are to: (1) Reduce new HIV, HCV, and syphilis infections to less than 3,000 per year by 2030; and (2) achieve a 90 percent reduction in new HCV infections and a 65 percent reduction in mortality, compared to a 2015 baseline.

129 days left
IHS
HHS-2026-IHS-TSGN-0001

Tribal Self-Governance Negotiation

The TSGP allows Tribes to negotiate with the IHS to assume Programs, Services, Functions, and Activities (PSFAs), in whole or in part. This gives Tribes the authority to manage and tailor health care programs to best suit the needs of their communities. Participation in the TSGP gives Tribes flexibility to tailor their health care needs by choosing one of three ways to get health care from the Federal Government for their citizens. Tribes can choose to: Get health care services directly from the IHS.Contract with the IHS to administer individual programs and services the IHS would otherwise provide (referred to as Title I Self-Determination Contracting).Compact with the IHS to assume control over health care programs the IHS would otherwise provide (referred to as Title V Self-Governance Compacting or the TSGP).These options are not exclusive. Tribes may choose to combine options based on their individual needs and circumstances.This Negotiation Cooperative Agreement’s purpose is to help Tribes cover the costs associated with preparing for and participating these negotiations.

58 days left
HHS-FDA
FOR-FD-26-003

Retail Food Safety Regulatory Association Collaboration

The program furthers the FDA's support of state, local, tribal, and territorial (SLTT) retail food safety programs in their efforts to reduce the occurrence of food-borne illness risk factors for the benefit of the public. Recipients of this funding will assist SLTT agencies in conducting research, implementing intervention strategies, and performing other activities to reduce the occurrence of food-borne illness risk factors, reduce the burden of foodborne illness, and advance a nationally integrated food safety system.

IHS
HHS-2025-IHS-ALZ-0001

Dementia CAReS Grants for American Indian and Alaska Native Communities

This is only a forecast. The synopsis and application package are not yet posted, and we have not yet finalized the application due date. This opportunity will be updated when it is published in Grants.gov. We want to achieve tangible, meaningful, and measurable action in every Tribal and Urban Indian community to positively impact the lives of people at risk of and living with dementia. This funding will support your efforts to design, implement, and promote activities nationally that help work towards that outcome. The four core strategies for this NOFO are to: · Provide “Mini-Grant” funding, training, technical assistance, and evaluation support to Tribal and Urban Indian clinical settings. Mini-Grant funding will support priority areas and address direct care, service, and training needs. Priority areas will be refined and finalized with us after the award. [AP(1] · Develop and support a “Call to Action” that identifies and connects a multi-disciplinary network of dementia champions and more broadly engages Tribal and Urban Indian communities. The Call to Action will help staff and communities learn from each other and work together to develop and achieve collective impact and improve outcomes. · Document and spread locally developed Tribal and Urban Indian Health emerging practices and success stories. The purpose is to increase awareness and promote innovation and change in clinical and community systems. Develop and implement an evaluation and data management plan, including the joint creation and testing of performance measures. The evaluation approach will track project [AP(1]Priority areas should be laid out in the application and guidance should be provided in the NOFO.

Up to $750K
HHS-FDA
FOR-FD-24-009

Flexible Funding Model-Infrastructure Development and Maintenance for State Manufactured Food Regulatory Programs (U2F) Clinical Trials Not Allowed

The intended outcome of this Notice of Funding Opportunity (NOFO) is to advance efforts for a nationally Integrated Food Safety System (IFSS) by supporting Manufactured Food Regulatory Program Standards (MFRPS), Food Protection Task Force (FPTF) programs, Dietary Supplement (DS) programs, and special projects. For the purposes of this NOFO, the term state encompasses all eligible organizations as defined in Section 3. MFRPS Development or Maintenance: The purpose of this Notice of Funding Opportunity (NOFO) section is to advance efforts for a nationally Integrated Food Safety System (IFSS) by assisting state manufactured food regulatory programs to achieve and maintain conformance with the most current version of the Manufactured Food Regulatory Program Standards (MFRPS). The MFRPS are intended to ensure that state manufactured food regulatory programs implement a high-quality regulatory program through the development and maintenance of a regulatory framework that builds on and emphasizes mutual reliance with all programs. Also, the program standards are intended to enhance food safety by establishing a uniform basis for measuring and improving the performance of manufactured food regulatory programs in the United States. Conformance with these program standards will help federal and state programs better direct their regulatory activities at reducing foodborne illness hazards in plants that manufacture, process, pack, or hold foods. Food Protection Task Force (FPTF): The purpose of this funding option is to establish and/or support a Food Protection Task Force (FPTF) with diverse membership representative of stakeholders across the state that is responsible for promoting the integration of an efficient statewide human and animal food (HAF) protection system that addresses state and region-specific needs and that maximize the protection of the public health. These efforts include: establishing a food safety/protection network of subject matter experts, fostering educational opportunities, developing replicable resources and systematically fostering communication, education, outreach, cooperation and collaboration within the states among federal, state, local, tribal and territorial HAF protection, public health, agriculture, and regulatory agencies, industry, academia, and consumers to initiate and/or support HAF protection activities to improve public health. A strong FPTF can also help improve human and animal food emergency surveillance, response, and post-response systems by focusing on preparedness, building strong communication channels, and establishing relationships with key players before food-related incidents occur. Dietary Supplements: The goal of this funding option is to facilitate the development of state driven dietary supplement regulatory framework and programs. The overall objective of this funding opportunity is to advance the adoption and implementation of the cGMPs for Dietary Supplements Rule codified at 21 CFR Part 111. Specifically, this track will provide funding support for dietary supplement training and program development activities. Special Projects: The purpose of this funding option is to develop and implement special projects that support innovation and integration in a IFSS using the MFRPS framework. This track will support other emerging food safety priorities that develop over the lifespan of the project. State programs will be expected to share project deliverables and resources developed with other programs.

Up to $1.3M
HHS-FDA
FOR-FD-24-001

Integrating Machine Learning with Computational Fluid Dynamics Models of Orally Inhaled Drug Products (U01) Clinical Trials Not Allowed

Computational fluid dynamics (CFD) has played a crucial role in providing an alternative bioequivalence (BE) approach for generic orally inhaled drug products (OIDPs), in addition to comparative clinical endpoint or pharmacodynamic BE studies, as a relatively cost- and time-efficient complement to benchtop and clinical experiments that has been widely used in developing and assessing generic inhaler devices. However, despite the advances in the power of modern computers, there are still some bottlenecks in using CFD due to computational time, limited grid resolution, pre- and post-processing of large simulation data sets, model parameter estimations, and uncertainty quantifications. Machine learning (ML) has been gaining more attention as a potential tool to alleviate such limitations that arise in CFD. The purpose of this grant is to develop a methodology to integrate ML with CFD models of OIDPs to promote alternative BE studies to enhance and accelerate the development and approval of generic OIDPs.

VA-CSHF
VA-GRANTS-112508-002

State Veterans Home Construction Grant Program

Improving Oversight of Federal GrantmakingVA is required to ensure compliance with all applicable statutes, regulations, and Executive Orders when evaluating and awarding grants. In accordance with Executive Order 14332, Improving Oversight of Federal Grantmaking, aside from the evaluation criteria published in this announcement, VA has discretion to remove from consideration any applicant VA deems does not clearly advance the President's or VA's priorities. VA will not fund activities that use racial preference for eligibility criteria or promote gender ideology. VA will not fund activities that promote or facilitate violations of immigration laws or are sources of waste, fraud, or abuse. VA will not tolerate activity or conduct by grant recipients that constitute acts of moral turpitude, are scandalous, or bring the recipient, the project funded by this grant, or VA into public disrepute, contempt, or ridicule. These grants support the President's priority to increase the excellence of and options for care, benefits, and services for veterans, as demonstrated in Executive Order 14332. Program is subject to Public Law 117-58 Build America, Buy America Act. Recipients of an award of Federal financial assistance from a program for infrastructure are hereby notified that none of the funds provided under this award may be used for a project for infrastructure unless:(1) all iron and steel used in the project are produced in the United States--this means all manufacturing processes, from the initial melting stage through the application of coatings, occurred in the United States; (2) all manufactured products used in the project are produced in the United States—this means the manufactured product was manufactured in the United States; and the cost of the components of the manufactured product that are mined, produced, or manufactured in the United States is greater than 55 percent of the total cost of all components of the manufactured product, unless another standard for determining the minimum amount of domestic content of the manufactured product has been established under applicable law or regulation; and (3) all construction materials44 are manufactured in the United States—this means that all manufacturing processes for the construction material occurred in the United States. The Buy America preference only applies to articles, materials, and supplies that are consumed in, incorporated into, or affixed to an infrastructure project. As such, it does not apply to tools, equipment, and supplies, such as temporary scaffolding, brought to the construction site and removed at or before the completion of the infrastructure project. Nor does a Buy America preference apply to equipment and furnishings, such as movable chairs, desks, and portable computer equipment, that are used at or within the finished infrastructure project, but are not an integral part of the structure or permanently affixed to the infrastructure project. Grants are available to State and Tribal Governments for construction or renovations of State/Tribal owned and operated Veterans Extended Care Facilities. The Department of Veterans Affairs participation may not exceed 65% of the total project costs. Review governing regulation before submitting an application (38 CFR Part 59). If the state is submitting a new grant application, it must submit a complete initial application (Section A of the project checklist) on Grants.gov by April 15th in order to be eligible for listing on the Priority List for the next fiscal year. Once the complete initial application is retrieved from Grants.gov by Program Staff, the grant applicant will receive 1) an automated notification from Grants.gov confirming receipt by the Program and 2) an email from Program Staff indicating the application's FAI number and corresponding project page in MAX.gov for submission of subsequent items. Note that Grants.gov is used only once to submit a new grant application. Applicants must submit complete initial applications on Grants.gov in order to be considered. Please contact Program Staff prior to submission if you need assistance understanding the requirements pertaining to an initial grant application, or if you need general assistance. Renovation or Life Safety initial grant applications require items A.1.-A.7. in Section A of the project checklist. Grant applicants, do not submit items A.8.-.A.13 for Renovation of Life Safety grants. Adult Day Health Care, New Home Construction or Bed Replacement initial grant applications require all items in Section A (A.1.-A.13) of the project checklist. Required for ALL applications A.1.A Project Scope A.1.B Form SF424 A.1.C Form SF424D A.1.D Form SF424C A.1.E Budget Justification Worksheet (must align with SF424C budget form) A.2. Governor's designation of authorized state official and contact person A.3. Needs assessment (as outlined in VA Form 10-0388-1) A.4. State Clearinghouse Comments (E.O. 12372) single point of contact and compliance statement A.5. Schematics A.6. Signed Initial Application Certification VA Form 10-0388-1 A.7. Safety citation/letter (Only Life Safety projects need to submit this). Required for Adult Day Health Care, Bed Replacement or New Construction - Items A1-A6 and the below items A.8. Space program analysis (NHC use Form 10-0388-3, ADHC use Form 10-0388-4) A.9. Five-year capital plan for state's entire state home program A.10. Financial plan for state facility's first three years of operation A.11. Documentation that there is a reasonable basis to conclude that the facility when complete will be fully occupied A.12. Authorized state official's certification of the total number of state-operated nursing home and domiciliary beds and occupancy rate A.13. Authorized state official's certification that the number of state home beds does not exceed the requirement in 38 CFR 59.40 or justification for number of state home beds exceeding 38 CFR 59.40 based on travel distance

Up to $275.0M